FP Inhibitor
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Treprostinil
0 ImagesSynonyms: UT-15Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
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PDC31
0 ImagesSynonyms: THG113.31; ILGHXDYKPDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor. PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine contractions in vivo, which can be used for research of preterm labor and primary dysmenorrhea (PD). PDC31 also enhances Ca2+-dependent large-conductance K+-channel in human myometrial cells.
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Darbufelone mesylate
0 ImagesSynonyms: CI-1004 mesylateDarbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50 = 0.19 μM) but is much less potent with PGHS-1 (IC50= 20 μM).
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CAY10535
0 ImagesCat. No.: HY-118014CAS No.: 945716-28-9CAY10535 is a FP and TP receptor inhibitor and can be used for research of cardiovascular diseases.
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CAY10509
0 ImagesCat. No.: HY-120752CAS No.: 1245699-47-1CAY10509 is a PGF2α analog and an inhibitor of the FP receptor with an IC50 of 30 nM. CAY10509 is promising for studying physiological regulatory mechanisms related to prostaglandins.
